On X, we can easily enable or disable input devices using the
xinput command. This is a great use case when you're tired of accidentally hitting the red Thinkpad nub or having your palm be recognized when drawing with a pen.
xinput command performs the action temporarily. Your default settings will be restored upon a reboot.
xinput devices run:
To disable a device:
xinput disable [id]
To enable a device:
xinput enable [id]
The ids are listed when you list the devices.